MATK anticorps (Internal Region)

N° du produit ABIN7222372

Cet anticorps Lapin Polyclonal détecte spécifiquement MATK dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MATK anticorps (Internal Region) (ABIN7222372)

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MATK anticorps

Épitope: Internal Region

Fonction: Lsk Polyclonal Antibody

Specificité: Lsk Polyclonal Antibody detects endogenous levels of Lsk protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Lsk

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: Lsk

Sujet: Rabbit Anti-Lsk Polyclonal Antibody,MATK, CTK, HYL, Megakaryocyte-associated tyrosine-protein kinase, CSK homologous kinase, CHK, Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK,The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: sRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.,Megakaryocyte-associated tyrosine-protein kinase

Poids moléculaire: observerd band 56kDa

ID gène: 4145

UniProt: P42679