MAGED2 anticorps (AA 120-200)

N° du produit ABIN7229540

Cet anticorps Lapin Polyclonal détecte spécifiquement MAGED2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MAGED2 anticorps (AA 120-200) (ABIN7229540)

Antigène: MAGED2 (Melanoma Antigen Family D, 2 (MAGED2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGED2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MAGED2 anticorps

Épitope: AA 120-200

Fonction: Rabbit Anti-MAGD2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MAGD2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MAGD2 protein at AA range: 120-200

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MAGED2

Antigène: MAGED2 (Melanoma Antigen Family D, 2 (MAGED2))

Autre désignation: MAGD2

Sujet: Melanoma-associated antigen D2, 11B6, Breast cancer-associated gene 1 protein, BCG-1, Hepatocellular carcinoma-associated protein JCL-1, MAGE-D2 antigenMAGED2 (MAGE Family Member D2) is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. MAGED2 is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in MAGED2 cause a form of transient antenatal Bartter's syndrome. MAGED2 may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by MAGED2 is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 66kD

ID gène: 10916

UniProt: Q9UNF1