Mesp2 anticorps (AA 220-300)

N° du produit ABIN7229648

Cet anticorps Lapin Polyclonal détecte spécifiquement Mesp2 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Mesp2 anticorps (AA 220-300) (ABIN7229648)

Antigène: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesp2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-Mesp2 anticorps

Épitope: AA 220-300

Fonction: Rabbit Anti-MESP2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MESP2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MESP2 protein at AA range: 220-300

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Mesp2

Antigène: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Autre désignation: MESP2

Sujet: Mesoderm posterior protein 2, Class C basic helix-loop-helix protein 6, bHLHc6MESP2 (Mesoderm Posterior BHLH Transcription Factor 2) is a Protein Coding gene. Diseases associated with MESP2 include Spondylocostal Dysostosis 2, Autosomal Recessive and Spondylocostal Dysostosis, Autosomal Recessive. Among its related pathways are Cardiac Progenitor Differentiation and Gene regulatory network modelling somitogenesis. MESP2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. MESP2 is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. MESP2 also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Poids moléculaire: 43kD

ID gène: 145873

UniProt: Q0VG99