MCPH1 anticorps (AA 60-140)

N° du produit ABIN7225086

L’anticorps anti-MCPH1 Polyclonal Lapin est utilisé pour la détection de MCPH1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour MCPH1 anticorps (AA 60-140) (ABIN7225086)

Antigène: MCPH1 (Microcephalin 1 (MCPH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCPH1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MCPH1 anticorps

Épitope: AA 60-140

Fonction: Rabbit Anti-Microcephalin Polyclonal Antibody

Specificité: Microcephalin Polyclonal Antibody detects endogenous levels of Microcephalin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human Microcephalin at AA range: 60-140

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MCPH1

Antigène: MCPH1 (Microcephalin 1 (MCPH1))

Autre désignation: Microcephalin

Sujet: MCPH1, MicrocephalinMCPH1 (microcephalin 1) encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in MCPH1 have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Poids moléculaire: 93kD

ID gène: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance