MID1 anticorps (AA 40-120)

N° du produit ABIN7215760

L’anticorps anti-MID1 Polyclonal produit chez le Lapin a été validé pour WB, ELISA, IF et IHC (p). Il convient pour la détection de MID1 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour MID1 anticorps (AA 40-120) (ABIN7215760)

Antigène: MID1 (Midline 1 (MID1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MID1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MID1 anticorps

Épitope: AA 40-120

Fonction: Midline-1 Polyclonal Antibody

Specificité: Midline-1 Polyclonal Antibody detects endogenous levels of Midline-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human Midline-1 at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MID1

Antigène: MID1 (Midline 1 (MID1))

Autre désignation: Midline-1

Sujet: Rabbit Anti-Midline-1 Polyclonal Antibody,MID1, FXY, RNF59, TRIM18, XPRF, Midline-1, Midin, Midline 1 RING finger protein, Putative transcription factor XPRF, RING finger protein 59, Tripartite motif-containing protein 18,Midline-1 encoded by this MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. Midline-1 is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing, however, the full-length nature of some of the variants has not been determined.,Midline-1

Poids moléculaire: observerd band 75kDa

ID gène: 4281

UniProt: O15344