MRPS18A anticorps (AA 50-130)

N° du produit ABIN7223394

L’anticorps anti-MRPS18A Polyclonal Lapin est utilisé pour la détection de MRPS18A dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour MRPS18A anticorps (AA 50-130) (ABIN7223394)

Antigène: MRPS18A (Mitochondrial Ribosomal Protein S18A (MRPS18A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPS18A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MRPS18A anticorps

Épitope: AA 50-130

Fonction: Rabbit Anti-MRP-S18A Polyclonal Antibody

Specificité: MRP-S18A Polyclonal Antibody detects endogenous levels of MRP-S18A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human MRP-S18A at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MRPS18A

Antigène: MRPS18A (Mitochondrial Ribosomal Protein S18A (MRPS18A))

Autre désignation: MRP-S18A

Sujet: MRPS18A, 28S ribosomal protein S18a, mitochondrial, MRP-S18-a, Mrps18a, S18mt-a, 28S ribosomal protein S18-3, mitochondrial, MRP-S18-3Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS18A (mitochondrial ribosomal protein S18A) encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to MRPS18A is found on chromosome 3p. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 27-30kD

ID gène: 55168

UniProt: Q9NVS2