Mps1 anticorps (pThr676)

N° du produit ABIN7224828

Cet anticorps anti-Mps1 Polyclonal Lapin (ABIN7224828) détecte spécifiquement Mps1 dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Mps1 anticorps (pThr676) (ABIN7224828)

Antigène: Mps1 (TTK)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mps1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Mps1 anticorps

Épitope: pThr676

Fonction: Rabbit Anti-TTK (phospho Thr676) Polyclonal Antibody

Specificité: Phospho-TTK (T676) Polyclonal Antibody detects endogenous levels of TTK protein only when phosphorylated at T676.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human TTK Phospho-Thr676

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Mps1

Antigène: Mps1 (TTK)

Autre désignation: TTK

Sujet: TTK, MPS1, MPS1L1, Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYTTTK (TTK protein kinase) encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

ID gène: 7272

UniProt: P33981