MDFIC anticorps (AA 100-180)
Aperçu rapide pour MDFIC anticorps (AA 100-180) (ABIN7229610)
Antigène
Voir toutes MDFIC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 100-180
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Fonction
- Rabbit Anti-MDFIC Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of MDFIC protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human MDFIC protein at AA range: 100-180
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))
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Autre désignation
- MDFIC
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Sujet
- MyoD family inhibitor domain-containing protein, I-mfa domain-containing protein, hICMDFIC (MyoD Family Inhibitor Domain Containing) is a Protein Coding gene. Diseases associated with MDFIC include T-Cell Leukemia and Hiv-1. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription. MDFIC product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.
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Poids moléculaire
- 27kD
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ID gène
- 29969
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UniProt
- Q9P1T7
Antigène
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