MYO3A anticorps (AA 180-260)

N° du produit ABIN7229858

Cet anticorps Lapin Polyclonal détecte spécifiquement MYO3A dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MYO3A anticorps (AA 180-260) (ABIN7229858)

Antigène: MYO3A (Myosin IIIA (MYO3A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO3A est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-MYO3A anticorps

Épitope: AA 180-260

Fonction: Rabbit Anti-MYO3A Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MYO3A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MYO3A protein at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MYO3A

Antigène: MYO3A (Myosin IIIA (MYO3A))

Autre désignation: MYO3A

Sujet: Myosin-IIIaMYO3A (Myosin IIIA) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. The protein encoded by MYO3A belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of MYO3A is highly restricted, with the strongest expression in retina and cochlea.

Poids moléculaire: 177kD

ID gène: 53904

UniProt: Q8NEV4

Pathways: Sensory Perception of Sound, Phototransduction