Myosin VIIA anticorps (AA 830-910)

N° du produit ABIN7229866

L’anticorps anti-Myosin VIIA Polyclonal Lapin est utilisé pour la détection de Myosin VIIA dans des échantillons de Humain et Souris. Il a été validé pour ELISA et WB.

Aperçu rapide pour Myosin VIIA anticorps (AA 830-910) (ABIN7229866)

Antigène: Myosin VIIA (MYO7A)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin VIIA est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-Myosin VIIA anticorps

Épitope: AA 830-910

Fonction: Rabbit Anti-MYO7A Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MYO7A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MYO7A protein at AA range: 830-910

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Myosin VIIA

Antigène: Myosin VIIA (MYO7A)

Autre désignation: MYO7A

Sujet: Unconventional myosin-VIIaMYO7A (Myosin VIIA) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. MYO7A is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. MYO7A encodes an unconventional myosin with a very short tail. Defects in MYO7A are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 243kD

ID gène: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound