NAD-ME anticorps (AA 180-260)

N° du produit ABIN7222420

Cet anticorps anti-NAD-ME Polyclonal Lapin (ABIN7222420) détecte spécifiquement NAD-ME dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour NAD-ME anticorps (AA 180-260) (ABIN7222420)

Antigène: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAD-ME est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NAD-ME anticorps

Épitope: AA 180-260

Fonction: Rabbit Anti-ME2 Polyclonal Antibody

Specificité: ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human ME2 at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NAD-ME

Antigène: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Autre désignation: ME2

Sujet: ME2, NAD-dependent malic enzyme, mitochondrial, NAD-ME, Malic enzyme 2ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Poids moléculaire: 65kD

ID gène: 4200

UniProt: P23368

Pathways: Production of Molecular Mediator of Immune Response