NANOS2 anticorps (AA 10-90)

N° du produit ABIN7229900

Cet anticorps anti-NANOS2 Polyclonal Lapin (ABIN7229900) détecte spécifiquement NANOS2 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour NANOS2 anticorps (AA 10-90) (ABIN7229900)

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANOS2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-NANOS2 anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-NANO2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of NANO2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human NANO2 protein at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NANOS2

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Autre désignation: NANO2

Sujet: Nanos homolog 2, NOS-2Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state (By similarity).

Poids moléculaire: 15kD

ID gène: 339345

UniProt: P60321

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance