NBR1 anticorps

N° du produit ABIN7212362

L’anticorps Souris Monoclonal anti-NBR1 a été validé pour IF et IHC (p). Il convient pour détecter NBR1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NBR1 anticorps (ABIN7212362)

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NBR1 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7C3

Détail du produit anti-NBR1 anticorps

Fonction: NBR1 Mouse Monoclonal Antibody (7C3)

Specificité: The antibody detects endogenous NBR1 protein.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogène: Recombinant Protein of NBR1

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur NBR1

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Autre désignation: NBR1

Sujet: Mouse Anti-NBR1 Mouse Monoclonal Antibody (7C3),Next to BRCA1 gene 1 protein, Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3B,The protein encoded by NBR1 (NBR1, autophagy cargo receptor) was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of NBR1 results in multiple transcript variants.,Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)

Poids moléculaire: observerd band 120kDa

ID gène: 4077

UniProt: Q14596

Pathways: Autophagy