NXF3 anticorps (AA 50-130)
Aperçu rapide pour NXF3 anticorps (AA 50-130) (ABIN7223602)
Antigène
Voir toutes NXF3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-130
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Fonction
- Rabbit Anti-NXF3 Polyclonal Antibody
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Specificité
- NXF3 Polyclonal Antibody detects endogenous levels of NXF3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human NXF3 at AA range: 50-130
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- NXF3 (Nuclear RNA Export Factor 3 (NXF3))
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Autre désignation
- NXF3
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Sujet
- NXF3, TAPL3, Nuclear RNA export factor 3, TAP-like protein 3, TAPL-3NXF3 (nuclear RNA export factor 3) is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
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Poids moléculaire
- 60kD
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ID gène
- 56000
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UniProt
- Q9H4D5
Antigène
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