OCRL anticorps (Internal Region)

N° du produit ABIN7216158

Cet anticorps Lapin Polyclonal détecte spécifiquement OCRL dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour OCRL anticorps (Internal Region) (ABIN7216158)

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OCRL est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-OCRL anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-OCRL Polyclonal Antibody

Specificité: OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human OCRL

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur OCRL

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Autre désignation: OCRL

Sujet: OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome proteinOCRL encodes an inositol polyphosphate 5-phosphatase. OCRL, inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. OCRL, inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation. Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 104kD

ID gène: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process