ORC2 anticorps (AA 180-260)

N° du produit ABIN7230402

Cet anticorps anti-ORC2 est un anticorps Lapin Polyclonal détectant ORC2 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour ORC2 anticorps (AA 180-260) (ABIN7230402)

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORC2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ORC2 anticorps

Épitope: AA 180-260

Fonction: ORC2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ORC2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human ORC2 protein at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ORC2

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Autre désignation: ORC2

Sujet: Rabbit Anti-ORC2 Polyclonal Antibody,Origin recognition complex subunit 2,ORC is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by ORC2 is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.,ORC2

Poids moléculaire: observerd band 63kDa

ID gène: 4999

UniProt: Q13416