Paired Box 3 anticorps (AA 150-230)
Aperçu rapide pour Paired Box 3 anticorps (AA 150-230) (ABIN7230508)
Antigène
Voir toutes Paired Box 3 (PAX3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 150-230
-
Fonction
- Rabbit Anti-PAX3 Polyclonal Antibody
-
Specificité
- The antibody detects endogenous levels of PAX3 protein
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- Synthesized peptide derived from part region of human PAX3 protein at AA range: 150-230
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- Paired Box 3 (PAX3)
-
Autre désignation
- PAX3
-
Sujet
- HuP2PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
-
Poids moléculaire
- 52kD
-
ID gène
- 5077
-
UniProt
- P23760
-
Pathways
- Sensory Perception of Sound, Tube Formation
Antigène
-