PHOX2B anticorps (AA 140-220)

N° du produit ABIN7230626

Cet anticorps Lapin Polyclonal détecte spécifiquement PHOX2B dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour PHOX2B anticorps (AA 140-220) (ABIN7230626)

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHOX2B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PHOX2B anticorps

Épitope: AA 140-220

Fonction: PHX2B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PHX2B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human PHX2B protein at AA range: 140-220

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PHOX2B

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Autre désignation: PHX2B

Sujet: Rabbit Anti-PHX2B Polyclonal Antibody,Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B,PHOX2B (Paired Like Homeobox 2b) is a Protein Coding gene. Diseases associated with PHOX2B include Central Hypoventilation Syndrome, Congenital and Neuroblastoma 2. Among its related pathways are Neural Crest Differentiation and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The DNA-associated protein encoded by PHOX2B is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. PHOX2B product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.,PHX2B

Poids moléculaire: observerd band 34kDa

ID gène: 8929

UniProt: Q99453