HRPT2 anticorps (AA 51-100)

N° du produit ABIN7230498

L’anticorps anti-HRPT2 Polyclonal Lapin est utilisé pour la détection de HRPT2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour HRPT2 anticorps (AA 51-100) (ABIN7230498)

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRPT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HRPT2 anticorps

Épitope: AA 51-100

Fonction: Rabbit Anti-Parafibromin Polyclonal Antibody

Specificité: This antibody detects endogenous levels of Parafibromin

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human Parafibromin protein at AA range: 51-100

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HRPT2

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Autre désignation: Parafibromin

Sujet: Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 proteinCDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in CDC73 have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Poids moléculaire: 60kD

ID gène: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance