PSPC1 anticorps (AA 10-90)

N° du produit ABIN7230818

Cet anticorps anti-PSPC1 Polyclonal Lapin (ABIN7230818) détecte spécifiquement PSPC1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PSPC1 anticorps (AA 10-90) (ABIN7230818)

Antigène: PSPC1 (Paraspeckle Component 1 (PSPC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSPC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PSPC1 anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-PSPC1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PSPC1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PSPC1 protein at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PSPC1

Antigène: PSPC1 (Paraspeckle Component 1 (PSPC1))

Autre désignation: PSPC1

Sujet: Paraspeckle component 1, Paraspeckle protein 1PSPC1 (Paraspeckle Component 1) is a Protein Coding gene. Diseases associated with PSPC1 include Eec Syndrome and Rapp-Hodgkin Syndrome. Among its related pathways are Circadian rythm related genes. PSPC1 encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by PSPC1 is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of PSPC1 results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

Poids moléculaire: 57kD

ID gène: 55269

UniProt: Q8WXF1