PAX3 and PAX7 Binding Protein 1 (PAXBP1) anticorps
Aperçu rapide pour PAX3 and PAX7 Binding Protein 1 (PAXBP1) anticorps (ABIN7228626)
Antigène
Voir toutes PAX3 and PAX7 Binding Protein 1 (PAXBP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- GCFC1 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of GCFC1 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human GCFC1 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PAX3 and PAX7 Binding Protein 1 (PAXBP1)
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Autre désignation
- GCFC1
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Sujet
- Rabbit Anti-GCFC1 Polyclonal Antibody,PAX3- and PAX7-binding protein 1, GC-rich sequence DNA-binding factor 1,PAXBP1 encodes the PAX3 And PAX7 Binding Protein 1 that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of Lys-4 of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity).,GCFC1
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Poids moléculaire
- observerd band 100kDa
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ID gène
- 94104
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UniProt
- Q9Y5B6
Antigène
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