PGLYRP2 anticorps

N° du produit ABIN7231698

Cet anticorps anti-PGLYRP2 Polyclonal Lapin (ABIN7231698) détecte spécifiquement PGLYRP2 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PGLYRP2 anticorps (ABIN7231698)

Antigène: PGLYRP2 (Peptidoglycan Recognition Protein 2 (PGLYRP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGLYRP2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-PGLYRP2 anticorps

Fonction: Rabbit Anti-TAGL Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TAGL protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TAGL protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PGLYRP2

Antigène: PGLYRP2 (Peptidoglycan Recognition Protein 2 (PGLYRP2))

Autre désignation: TAGL

Sujet: Transgelin, 22 kDa actin-binding protein, Protein WS3-10, Smooth muscle protein 22-alpha, SM22-alphaTAGLN encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization.

Poids moléculaire: 22kD

ID gène: 6876

UniProt: Q01995

Pathways: Activation of Innate immune Response, Glycosaminoglycan Metabolic Process