PCM1 anticorps (AA 140-220)

N° du produit ABIN7230526

Cet anticorps anti-PCM1 est un anticorps Lapin Polyclonal détectant PCM1 dans WB et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour PCM1 anticorps (AA 140-220) (ABIN7230526)

Antigène: PCM1 (Pericentriolar Material 1 (PCM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PCM1 anticorps

Épitope: AA 140-220

Fonction: PCM1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PCM1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human PCM1 protein at AA range: 140-220

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PCM1

Antigène: PCM1 (Pericentriolar Material 1 (PCM1))

Autre désignation: PCM1

Sujet: Rabbit Anti-PCM1 Polyclonal Antibody,Pericentriolar material 1 protein, PCM-1, hPCM-1,PCM1 (Pericentriolar Material 1) is a Protein Coding gene. Diseases associated with PCM1 include Differentiated Thyroid Carcinoma and Atypical Chronic Myeloid Leukemia. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. The protein encoded by PCM1 is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for PCM1.,PCM1

Poids moléculaire: observerd band 222kDa

ID gène: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location