PER2 anticorps (pSer662)
Aperçu rapide pour PER2 anticorps (pSer662) (ABIN7225694)
Antigène
Voir toutes PER2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer662
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Fonction
- Rabbit Anti-Per2 (phospho Ser662) Polyclonal Antibody
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Specificité
- Phospho-Per2 (S662) Polyclonal Antibody detects endogenous levels of Per2 protein only when phosphorylated at S662.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human Per2 Phospho-Ser662
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PER2 (Period Circadian Protein 2 (PER2))
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Autre désignation
- Per2
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Sujet
- PER2, KIAA0347, Period circadian protein homolog 2, hPER2, Circadian clock protein PERIOD 2PER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER2 may increase the risk of getting certain cancers and have been linked to sleep disorders.
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Poids moléculaire
- 120kD
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ID gène
- 8864
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UniProt
- O15055
Antigène
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