PER1 anticorps (AA 1110-1190)

N° du produit ABIN7230586

L’anticorps anti-PER1 Polyclonal Lapin est utilisé pour la détection de PER1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour PER1 anticorps (AA 1110-1190) (ABIN7230586)

Antigène: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PER1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PER1 anticorps

Épitope: AA 1110-1190

Fonction: Rabbit Anti-PER1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PER1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PER1 protein at AA range: 1110-1190

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PER1

Antigène: PER1 (Period Homolog 1 (Drosophila) (PER1))

Autre désignation: PER1

Sujet: Period circadian protein homolog 1, hPER1, Circadian clock protein PERIOD 1, Circadian pacemaker protein RiguiPER1 is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER1 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER1 may increase the risk of getting certain cancers. Alternative splicing has been observed in PER1, however, these variants have not been fully described.

Poids moléculaire: 141kD

ID gène: 5187

UniProt: O15534

Pathways: Photoperiodism