PGE Synthase anticorps (Internal Region)
Aperçu rapide pour PGE Synthase anticorps (Internal Region) (ABIN7216522)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- Rabbit Anti-PGE synthase Polyclonal Antibody
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Specificité
- PGE synthase Polyclonal Antibody detects endogenous levels of PGE synthase protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human PGE synthase
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PGE Synthase
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Sujet
- PTGES, MGST1L1, MPGES1, PGES, PIG12, Prostaglandin E synthase, Microsomal glutathione S-transferase 1-like 1, MGST1-L1, Microsomal prostaglandin E synthase 1, MPGES-1, p53-induced gene 12 proteinProstaglandin E synthase encoded by PTGES is a glutathione-dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
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Poids moléculaire
- 17kD
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ID gène
- 9536
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UniProt
- O14684
Antigène
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