PEBP1 anticorps (AA 71-120)
Aperçu rapide pour PEBP1 anticorps (AA 71-120) (ABIN7230514)
Antigène
Voir toutes PEBP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 71-120
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Fonction
- Rabbit Anti-PBP Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of PBP
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human PBP protein at AA range: 71-120
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
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Autre désignation
- PBP
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Sujet
- Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7The protein encoded by PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Essential Thrombocythemia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and p70S6K Signaling.
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ID gène
- 5473
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UniProt
- P02775
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Pathways
- Feeding Behaviour
Antigène
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