PIGC anticorps (AA 170-250)

N° du produit ABIN7230640

Cet anticorps Lapin Polyclonal détecte spécifiquement PIGC dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PIGC anticorps (AA 170-250) (ABIN7230640)

Antigène: PIGC (Phosphatidylinositol Glycan C (PIGC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIGC est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-PIGC anticorps

Épitope: AA 170-250

Fonction: Rabbit Anti-PIGC Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PIGC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PIGC protein at AA range: 170-250

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PIGC

Antigène: PIGC (Phosphatidylinositol Glycan C (PIGC))

Autre désignation: PIGC

Sujet: Phosphatidylinositol N-acetylglucosaminyltransferase subunit C, Phosphatidylinositol-glycan biosynthesis class C protein, PIG-CPIGC (Phosphatidylinositol Glycan Anchor Biosynthesis Class C) is a Protein Coding gene. Diseases associated with PIGC include Autosomal Recessive Non-Syndromic Intellectual Disability and Lassa Fever. Among its related pathways are Glycosylphosphatidylinositol (GPI)-anchor biosynthesis and Metabolism. PIGC encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for PIGC. A pseudogene on chromosome 11 has also been characterized.

Poids moléculaire: 32kD

ID gène: 5279

UniProt: Q92535

Pathways: Inositol Metabolic Process