PREX1 anticorps (AA 340-420)

N° du produit ABIN7230776

Cet anticorps anti-PREX1 est un anticorps Lapin Polyclonal détectant PREX1 dans ELISA et WB. Adapté pour Humain et Souris.

Aperçu rapide pour PREX1 anticorps (AA 340-420) (ABIN7230776)

Antigène: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PREX1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-PREX1 anticorps

Épitope: AA 340-420

Fonction: PREX1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PREX1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human PREX1 protein at AA range: 340-420

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PREX1

Antigène: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Autre désignation: PREX1

Sujet: Rabbit Anti-PREX1 Polyclonal Antibody,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,4,5)-dependent Rac exchanger 1,PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 1) is a Protein Coding gene. Diseases associated with PREX1 include Luminal Breast Carcinoma. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. The protein encoded by PREX1 acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.,PREX1

Poids moléculaire: observerd band 182kDa

ID gène: 57580

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization