PDE3B anticorps

N° du produit ABIN7230558

Cet anticorps anti-PDE3B est un anticorps Lapin Polyclonal détectant PDE3B dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour PDE3B anticorps (ABIN7230558)

Antigène: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE3B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PDE3B anticorps

Fonction: PDE3B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PDE3B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human PDE3B protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PDE3B

Antigène: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Autre désignation: PDE3B

Sujet: Rabbit Anti-PDE3B Polyclonal Antibody,cGMP-inhibited 3',5'-cyclic phosphodiesterase B, CGIPDE1, CGIP1, Cyclic GMP-inhibited phosphodiesterase B, CGI-PDE B,PDE3B (Phosphodiesterase 3B) is a Protein Coding gene. Diseases associated with PDE3B include Pseudohypoparathyroidism, Type Ii and Pelizaeus-Merzbacher Disease. Among its related pathways are G alpha(s) signalling events and Akt Signaling. Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.,PDE3B

Poids moléculaire: observerd band 122kDa

ID gène: 5140

UniProt: Q13370

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process