PDE3B anticorps

N° du produit ABIN7230558

Cet anticorps anti-PDE3B Polyclonal Lapin (ABIN7230558) détecte spécifiquement PDE3B dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PDE3B anticorps (ABIN7230558)

Antigène: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE3B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PDE3B anticorps

Fonction: Rabbit Anti-PDE3B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PDE3B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PDE3B protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDE3B

Antigène: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Autre désignation: PDE3B

Sujet: CGMP-inhibited 3',5'-cyclic phosphodiesterase B, CGIPDE1, CGIP1, Cyclic GMP-inhibited phosphodiesterase B, CGI-PDE BPDE3B (Phosphodiesterase 3B) is a Protein Coding gene. Diseases associated with PDE3B include Pseudohypoparathyroidism, Type Ii and Pelizaeus-Merzbacher Disease. Among its related pathways are G alpha(s) signalling events and Akt Signaling. Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Poids moléculaire: 122kD

ID gène: 5140

UniProt: Q13370

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process