PDE4B/C/D anticorps
Aperçu rapide pour PDE4B/C/D anticorps (ABIN7216474)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-PDE4B/C/D Polyclonal Antibody
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Specificité
- PDE4B/C/D Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human PDE4B/C/D around the non-phosphorylation site of S133/119/190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))
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Autre désignation
- PDE4B/C/D
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Sujet
- PDE4B, DPDE4, cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4C, DPDE1, cAMP-specific 3',5'-cyclic phosphodiesterase 4C, DPDE1, PDE21, PDE4D, DPDE3, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, DPDE3, PDE43PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. PDE4D uses different promoters to generate multiple alternatively spliced transcript variants that encode functiona.
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Poids moléculaire
- 76kD
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ID gène
- 5144, 5142, 5143
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UniProt
- Q07343, Q08493, Q08499
Antigène
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