PDE4C anticorps (AA 260-340)

N° du produit ABIN7216476

Cet anticorps anti-PDE4C Polyclonal Lapin (ABIN7216476) détecte spécifiquement PDE4C dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PDE4C anticorps (AA 260-340) (ABIN7216476)

Antigène: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PDE4C anticorps

Épitope: AA 260-340

Fonction: Rabbit Anti-PDE4C Polyclonal Antibody

Specificité: PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human PDE4C at AA range: 260-340

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDE4C

Antigène: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Autre désignation: PDE4C

Sujet: PDE4C, DPDE1, cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.

Poids moléculaire: 80kD

ID gène: 5143

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process