PDE7A anticorps

N° du produit ABIN7230562

L’anticorps anti-PDE7A Polyclonal Lapin est utilisé pour la détection de PDE7A dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour PDE7A anticorps (ABIN7230562)

Antigène: PDE7A (phosphodiesterase 7A (PDE7A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE7A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PDE7A anticorps

Fonction: Rabbit Anti-PDE7A Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PDE7A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PDE7A protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDE7A

Antigène: PDE7A (phosphodiesterase 7A (PDE7A))

Autre désignation: PDE7A

Sujet: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, HCP1, TM22The protein encoded by PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE7A. PDE7A (Phosphodiesterase 7A) is a Protein Coding gene. Diseases associated with PDE7A include Chronic Lymphocytic Leukemia and Low Compliance Bladder. Among its related pathways are G alpha(s) signalling events and Ectoderm Differentiation.

Poids moléculaire: 53kD

ID gène: 5150

UniProt: Q13946

Pathways: cAMP Metabolic Process