PI3K p101 anticorps (AA 670-750)

N° du produit ABIN7220738

Cet anticorps Lapin Polyclonal détecte spécifiquement PI3K p101 dans ELISA, IHC, WB et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour PI3K p101 anticorps (AA 670-750) (ABIN7220738)

Antigène: PI3K p101 (Phosphoinositide 3 Kinase, p101 (PI3K p101))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PI3K p101 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PI3K p101 anticorps

Épitope: AA 670-750

Fonction: Rabbit Anti-PI 3-kinase p101 Polyclonal Antibody

Specificité: PI 3-kinase p101 Polyclonal Antibody detects endogenous levels of PI 3-kinase p101 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human PI 3-kinase p101 at AA range: 670-750

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PI3K p101

Antigène: PI3K p101 (Phosphoinositide 3 Kinase, p101 (PI3K p101))

Autre désignation: PI 3-kinase p101

Sujet: PIK3R5, Phosphoinositide 3-kinase regulatory subunit 5, PI3-kinase regulatory subunit 5, PI3-kinase p101 subunit, Phosphatidylinositol 4, 5-bisphosphate 3-kinase regulatory subunit, PtdIns-3-kinase regulatory subunit, Protein FOAP-2, PtdIns-Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: i, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

Poids moléculaire: 100kD

ID gène: 23533

UniProt: Q8WYR1