PIM1 anticorps (pTyr309)

N° du produit ABIN7223146

L’anticorps anti-PIM1 Polyclonal Lapin est utilisé pour la détection de PIM1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour PIM1 anticorps (pTyr309) (ABIN7223146)

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PIM1 anticorps

Épitope: pTyr309

Fonction: Pim-1 (phospho Tyr309) Polyclonal Antibody

Specificité: Phospho-Pim-1 (Y309) Polyclonal Antibody detects endogenous levels of Pim-1 protein only when phosphorylated at Y309.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Pim-1 Phospho-Tyr309

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PIM1

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Autre désignation: Pim-1

Sujet: Rabbit Anti-Pim-1 (phospho Tyr309) Polyclonal Antibody,PIM1, Serine/threonine-protein kinase pim-1,The protein encoded by PIM1 (Pim-1 proto-oncogene, serine/threonine kinase) belongs to the Ser/Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.,serine threonine-protein kinase pim-1

Poids moléculaire: observerd band 45kDa

ID gène: 5292

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process