PIM1 anticorps

N° du produit ABIN7223148

Cet anticorps anti-PIM1 Polyclonal Lapin (ABIN7223148) détecte spécifiquement PIM1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PIM1 anticorps (ABIN7223148)

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PIM1 anticorps

Fonction: Rabbit Anti-Pim-1 Polyclonal Antibody

Specificité: Pim-1 Polyclonal Antibody detects endogenous levels of Pim-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Pim-1 around the non-phosphorylation site of Y309

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PIM1

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Autre désignation: Pim-1

Sujet: PIM1, Serine/threonine-protein kinase pim-1The protein encoded by PIM1 (Pim-1 proto-oncogene, serine/threonine kinase) belongs to the Ser/Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

Poids moléculaire: 50kD

ID gène: 5292

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process