Plastin 3 anticorps (AA 180-260)

N° du produit ABIN7230702

Cet anticorps Lapin Polyclonal détecte spécifiquement Plastin 3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Plastin 3 anticorps (AA 180-260) (ABIN7230702)

Antigène: Plastin 3 (PLS3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Plastin 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Plastin 3 anticorps

Épitope: AA 180-260

Fonction: Rabbit Anti-PLS3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PLS3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PLS3 protein at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Plastin 3

Antigène: Plastin 3 (PLS3)

Autre désignation: PLS3

Sujet: Phospholipid scramblase 3, PL scramblase 3, Ca(2+)-dependent phospholipid scramblase 3May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Poids moléculaire: 32kD

ID gène: 57048

UniProt: Q9NRY6