PVRL4 anticorps (AA 290-370)

N° du produit ABIN7225202

Cet anticorps Lapin Polyclonal détecte spécifiquement PVRL4 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour PVRL4 anticorps (AA 290-370) (ABIN7225202)

Antigène: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PVRL4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PVRL4 anticorps

Épitope: AA 290-370

Fonction: Rabbit Anti-Nectin 4 Polyclonal Antibody

Specificité: Nectin 4 Polyclonal Antibody detects endogenous levels of Nectin 4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Nectin 4 at AA range: 290-370

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PVRL4

Antigène: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Autre désignation: Nectin 4

Sujet: PVRL4, LNIR, PRR4, Poliovirus receptor-related protein 4, Ig superfamily receptor LNIR, Nectin-4NECTIN4 (nectin cell adhesion molecule 4) encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in NECTIN4 are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Poids moléculaire: 55kD

ID gène: 81607

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization