PKD2 anticorps (pSer812)

N° du produit ABIN7223162

Cet anticorps Lapin Polyclonal détecte spécifiquement PKD2 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PKD2 anticorps (pSer812) (ABIN7223162)

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PKD2 anticorps

Épitope: pSer812

Fonction: Rabbit Anti-PKD2 (phospho Ser812) Polyclonal Antibody

Specificité: Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human PKD2 Phospho-Ser812

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: PKD2

Sujet: PKD2, Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321PKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in PKD2 are associated with autosomal dominant polycystic kidney disease type 2.

ID gène: 5311

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity