PNPT1 anticorps (AA 540-620)
Aperçu rapide pour PNPT1 anticorps (AA 540-620) (ABIN7216622)
Antigène
Voir toutes PNPT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 540-620
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Fonction
- Rabbit Anti-PNPase Polyclonal Antibody
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Specificité
- PNPase Polyclonal Antibody detects endogenous levels of PNPase protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the C-terminal region of human PNPase at AA range: 540-620
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PNPT1 (Polyribonucleotide Nucleotidyltransferase 1 (PNPT1))
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Autre désignation
- PNPase
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Sujet
- PNPT1, PNPASE, Polyribonucleotide nucleotidyltransferase 1, mitochondrial, 3'-5' RNA exonuclease OLD35, PNPase old-35, Polynucleotide phosphorylase 1, PNPase 1, Polynucleotide phosphorylase-like proteinPolyribonucleotide nucleotidyltransferase 1 encoded by PNPT1 elongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. Polyribonucleotide nucleotidyltransferase 1 is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.
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Poids moléculaire
- 85kD
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ID gène
- 87178
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UniProt
- Q8TCS8
Antigène
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