PDCD10 anticorps (AA 40-120)

N° du produit ABIN7230538

L’anticorps anti-PDCD10 Polyclonal Lapin est utilisé pour la détection de PDCD10 dans des échantillons de Humain, Rat et Souris. Il a été validé pour ELISA et WB.

Aperçu rapide pour PDCD10 anticorps (AA 40-120) (ABIN7230538)

Antigène: PDCD10 (Programmed Cell Death 10 (PDCD10))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDCD10 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-PDCD10 anticorps

Épitope: AA 40-120

Fonction: Rabbit Anti-PDC10 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PDC10 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PDC10 protein at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDCD10

Antigène: PDCD10 (Programmed Cell Death 10 (PDCD10))

Autre désignation: PDC10

Sujet: Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15PDCD10 encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in PDCD10 are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 23kD

ID gène: 11235

UniProt: Q9BUL8