PPP1R16A anticorps (AA 340-420)

N° du produit ABIN7225488

L’anticorps anti-PPP1R16A Polyclonal Lapin est utilisé pour la détection de PPP1R16A dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour PPP1R16A anticorps (AA 340-420) (ABIN7225488)

Antigène: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R16A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PPP1R16A anticorps

Épitope: AA 340-420

Fonction: Rabbit Anti-MYPT3 Polyclonal Antibody

Specificité: MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human MYPT3 at AA range: 340-420

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF/ICC1:50-200,ELISA 1:2000-20000,IHC 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PPP1R16A

Antigène: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Autre désignation: MYPT3

Sujet: PPP1R16A, MYPT3, Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by MYPT3 (protein phosphatase 1 regulatory subunit 16A, PPP1R16A) represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.

Poids moléculaire: 60kD

ID gène: 84988

UniProt: Q96I34