SPDEF/PSE anticorps (AA 140-220)
Aperçu rapide pour SPDEF/PSE anticorps (AA 140-220) (ABIN7231488)
Antigène
Voir toutes SPDEF/PSE (SPDEF) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 140-220
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Fonction
- Rabbit Anti-SPDEF Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SPDEF protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human SPDEF protein at AA range: 140-220
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
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Autre désignation
- SPDEF
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Sujet
- SAM pointed domain-containing Ets transcription factor, Prostate epithelium-specific Ets transcription factor, Prostate-specific Ets, Prostate-derived Ets factorThe protein encoded by SPDEF belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for SPDEF.
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Poids moléculaire
- 36kD
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ID gène
- 25803
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UniProt
- O95238
Antigène
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