RAB11FIP2 anticorps (AA 310-390)
Aperçu rapide pour RAB11FIP2 anticorps (AA 310-390) (ABIN7220550)
Antigène
Voir toutes RAB11FIP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 310-390
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Fonction
- Rabbit Anti-Rab11-FIP2 Polyclonal Antibody
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Specificité
- Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human Rab11-FIP2 at AA range: 310-390
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))
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Autre désignation
- Rab11-FIP2
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Sujet
- RAB11FIP2, KIAA0941, Rab11 family-interacting protein 2, Rab11-FIP2, NRip11A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
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Poids moléculaire
- 58kD
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ID gène
- 22841
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UniProt
- Q7L804
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Antigène
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