RAB13 anticorps (AA 40-120)
Aperçu rapide pour RAB13 anticorps (AA 40-120) (ABIN7230870)
Antigène
Voir toutes RAB13 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-120
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Fonction
- Rabbit Anti-RAB13 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RAB13 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human RAB13 protein at AA range: 40-120
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- RAB13 (RAB13, Member RAS Oncogene Family (RAB13))
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Autre désignation
- RAB13
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Sujet
- Ras-related protein Rab-13, Cell growth-inhibiting gene 4 proteinRAB13 (RAB13, Member RAS Oncogene Family) is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for RAB13. A pseudogene associated with RAB13 is located on chromosome 12.
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Poids moléculaire
- 22kD
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ID gène
- 5872
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UniProt
- P51153
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Pathways
- Cell-Cell Junction Organization
Antigène
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