RAB33B anticorps (AA 100-180)

N° du produit ABIN7230960

Cet anticorps Lapin Polyclonal détecte spécifiquement RAB33B dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour RAB33B anticorps (AA 100-180) (ABIN7230960)

Antigène: RAB33B (RAB33B, Member RAS Oncogene Family (RAB33B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB33B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAB33B anticorps

Épitope: AA 100-180

Fonction: Rabbit Anti-RB33B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RB33B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RB33B protein at AA range: 100-180

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAB33B

Antigène: RAB33B (RAB33B, Member RAS Oncogene Family (RAB33B))

Autre désignation: RB33B

Sujet: Ras-related protein Rab-33BRAB33B (RAB33B, Member RAS Oncogene Family) encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by RAB33B is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in RAB33B have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities.

Poids moléculaire: 25kD

ID gène: 83452

UniProt: Q9H082