RAB3IP anticorps (AA 230-310)
Aperçu rapide pour RAB3IP anticorps (AA 230-310) (ABIN7219372)
Antigène
Voir toutes RAB3IP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 230-310
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Fonction
- RAB3IP Polyclonal Antibody
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Specificité
- RAB3IP Polyclonal Antibody detects endogenous levels of RAB3IP protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human RAB3IP at AA range: 230-310
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))
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Autre désignation
- RAB3IP
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Sujet
- Rabbit Anti-RAB3IP Polyclonal Antibody,RAB3IP, RABIN8, Rab-3A-interacting protein, Rab3A-interacting protein, Rabin-3, SSX2-interacting protein,Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.,Rab-3A-interacting protein
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Poids moléculaire
- observerd band 53kDa
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ID gène
- 117177
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UniProt
- Q96QF0
Antigène
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