RAB3IP anticorps (AA 230-310)

N° du produit ABIN7219372

L’anticorps anti-RAB3IP Polyclonal Lapin est utilisé pour la détection de RAB3IP dans des échantillons de Humain, Rat et Souris. Il a été validé pour ELISA, IHC, WB et IF.

Aperçu rapide pour RAB3IP anticorps (AA 230-310) (ABIN7219372)

Antigène: RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB3IP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RAB3IP anticorps

Épitope: AA 230-310

Fonction: Rabbit Anti-RAB3IP Polyclonal Antibody

Specificité: RAB3IP Polyclonal Antibody detects endogenous levels of RAB3IP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human RAB3IP at AA range: 230-310

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAB3IP

Antigène: RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))

Autre désignation: RAB3IP

Sujet: RAB3IP, RABIN8, Rab-3A-interacting protein, Rab3A-interacting protein, Rabin-3, SSX2-interacting proteinGuanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

Poids moléculaire: 53kD

ID gène: 117177

UniProt: Q96QF0