REPS2 anticorps (AA 390-470)
Aperçu rapide pour REPS2 anticorps (AA 390-470) (ABIN7230998)
Antigène
Voir toutes REPS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 390-470
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Fonction
- Rabbit Anti-REPS2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of REPS2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human REPS2 protein at AA range: 390-470
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))
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Autre désignation
- REPS2
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Sujet
- RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2The product of REPS2 (RALBP1 Associated Eps Domain Containing 2) is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for REPS2.
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Poids moléculaire
- 72kD
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ID gène
- 9185
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UniProt
- Q8NFH8
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Pathways
- EGFR Signaling Pathway
Antigène
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